Prevalence of equine herpesvirus type 1 strains of neuropathogenic genotype in a major breeding area of Japan.
J Vet Med Sci
; 73(12): 1663-7, 2011 Dec.
Article
em En
| MEDLINE
| ID: mdl-21828961
ABSTRACT
A single non-synonymous nucleotide substitution of guanine (G) for adenine (A) at position 2254 in the viral DNA polymerase gene (encoded by open reading frame [ORF] 30) of equine herpesvirus type 1 (EHV-1) has been significantly associated with neuropathogenic potential in strains of this virus. To estimate the prevalence of EHV-1 strains with the neuropathogenic genotype (ORF30 G(2254)) in the Hidaka district--a major horse breeding area in Japan--we analyzed the ORF30 genomic region in cases of EHV-1 infection in this area during the years 2001-2010. Of the 113 cases analyzed, 3 (2.7%) were induced by ORF30 G(2254) strains. This prevalence is lower than those observed in the U.S.A. (10.8-19.4%), Argentina (7.4%), France (24%), and Germany (10.6%).
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cruzamento
/
Herpesvirus Equídeo 1
/
Infecções por Herpesviridae
/
Doenças dos Cavalos
Tipo de estudo:
Prevalence_studies
/
Risk_factors_studies
Limite:
Animals
/
Pregnancy
País/Região como assunto:
Asia
Idioma:
En
Revista:
J Vet Med Sci
Ano de publicação:
2011
Tipo de documento:
Article