Outcome of Chlamydia pneumoniae associated acute ischemic stroke in elderly patients: a case-control study.
Clin Neurol Neurosurg
; 114(2): 120-3, 2012 Feb.
Article
em En
| MEDLINE
| ID: mdl-22030154
ABSTRACT
BACKGROUND:
Limited data exists about the role of Chlamydia pneumoniae elderly patients with acute ischemic stroke.OBJECTIVE:
To study the role of C. pneumoniae in elderly patients (age more than 65 years) with acute ischemic stroke and its impact on stroke out come.METHODS:
We recruited 100 elderly patients with acute ischemic stroke and 100 age and sex matched controls over a period of 2 years. IgG and IgA anti C. pneumoniae antibodies were measured by microimmunofluorescence technique in patients and controls. Good outcome was defined as a Modified Rankin score (mRS) of ≤2.RESULTS:
We found C. pneumoniae antibodies in 35% stroke patients and in 18% control subjects (p=0.01). Good out come at 90 days follow up was found in 20/35(57.1%) seropositive stroke patients compared to 37/65(56.9%) seronegative stroke patients (p=0.9).CONCLUSIONS:
C. pneumoniae antibody positivity was independently associated with ischemic stroke in elderly patients and its presence does not alter the stroke outcome.
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
1_ASSA2030
/
2_ODS3
Base de dados:
MEDLINE
Assunto principal:
Infecções por Chlamydia
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Isquemia Encefálica
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Chlamydophila pneumoniae
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Acidente Vascular Cerebral
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Aged
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Aged80
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Female
/
Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Clin Neurol Neurosurg
Ano de publicação:
2012
Tipo de documento:
Article