Obstructive colon metastases from lobular breast cancer: report of a case and review of the literature.
Tumori
; 97(6): 800-4, 2011.
Article
em En
| MEDLINE
| ID: mdl-22322849
ABSTRACT
INTRODUCTION:
Gastrointestinal metastases from breast cancer are rare. One large series reported a rate of 0.7% of gastrointestinal metastatic manifestations from breast cancer, but its true incidence could be underestimated. Here we report a case of bowel obstruction caused by sigmoid metastases from breast cancer and describe its relevance to histological origin and clinical practice.METHODS:
The clinical course and histopathology of the case are reviewed and compared with reports of similar cases in the literature.RESULTS:
An 80-year-old woman presented with bowel obstruction. Her medical history included infiltrating lobular breast cancer treated with left radical mastectomy 25 years before the current presentation; 13 years later bone metastases developed and were treated with hormone therapy. In 2003 the patient came to our emergency department because of symptoms of bowel obstruction. A computed tomography (CT) scan revealed a mass in the distal sigmoid causing the obstruction. A colostomy was performed, followed by a second operation completed with Hartmann's procedure. Histological examination revealed metastases from invasive lobular carcinoma. The patient was discharged 45 days postoperatively and died 9 months later because of disease progression.CONCLUSIONS:
Although gastrointestinal metastases from breast cancer are rare, patients with diagnosed breast cancer, particularly invasive lobular carcinoma, should be regularly followed up with endoscopy, CT, endosonography and PET-CT when abdominal symptoms are present. This could permit early diagnosis of gastrointestinal metastases and improve treatment planning.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias do Colo Sigmoide
/
Neoplasias da Mama
/
Carcinoma Lobular
/
Obstrução Intestinal
Tipo de estudo:
Screening_studies
Limite:
Aged80
/
Female
/
Humans
Idioma:
En
Revista:
Tumori
Ano de publicação:
2011
Tipo de documento:
Article