Unraveling the Numerous Biosynthetic Products of the Marine Sediment-Derived Fungus, Aspergillus insulicola.
Phytochem Lett
; 5(1): 114-117, 2012 Mar 01.
Article
em En
| MEDLINE
| ID: mdl-22368725
ABSTRACT
A new tripeptide, pre-sclerotiotide F (3), was isolated from a marine sediment-derived fungus, Aspergillus insulicola, along with five known compounds, one of which was new at the time of isolation, scerotiotide F (4). The absolute configuration elucidation of the new compound was determined using a combination of NMR, HR-ESI-MS, and optical rotation analyses. Cytotoxicities were measured in vitro against selected cancer cells. The effects of pre-sclerotiotide F (3) and sclerotiotide F (4) on LPS-induced NF-κB and iNOS expression were also measured.
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01-internacional
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MEDLINE
Idioma:
En
Revista:
Phytochem Lett
Ano de publicação:
2012
Tipo de documento:
Article