Childhood trajectories of anxiousness and disruptiveness explain the association between early-life adversity and attempted suicide.
Psychol Med
; 42(11): 2373-82, 2012 Nov.
Article
em En
| MEDLINE
| ID: mdl-22433421
ABSTRACT
BACKGROUND:
Suicidal behavior is frequently associated with a history of childhood abuse yet it remains unclear precisely how early life adversity may increase suicide risk later in life. As such, our aim was to examine whether lifetime trajectories of disruptiveness and anxiousness trait dysregulation explain the association between childhood adversity and suicidal behavior; and moreover, to test the potential modifying effects of mental disorders on these associations.METHOD:
A sample of 1776 individuals from a prospective school-based cohort followed longitudinally for over 22 years was investigated. We tested the influence of disruptiveness and anxiousness trajectories from age 6 to 12 years on the association between childhood adversity (i.e. sexual and physical abuse) and history of suicide attempts (SA) using logistic regression models. Both adolescent externalizing and internalizing Axis I disorders and gender were tested as potential modifiers of these associations.RESULTS:
Four distinct longitudinal trajectories were identified for both disruptiveness and anxiousness. The high disruptiveness trajectory accounted for the association between childhood adversity and SA, but only for females. The high anxiousness trajectory also explained the association between adversity and SA; however, in this case it was not sex but mental disorders that influenced the potency of the mediating effect. More specifically, anxiousness fully explained the effect of adversity on SA in the presence of externalizing disorders, whereas in the absence of these disorders, this effect was significantly attenuated.CONCLUSIONS:
This study provides evidence that both disruptiveness and anxiousness play an important role in explaining the relationship between childhood adversity and SA.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ansiedade
/
Tentativa de Suicídio
/
Maus-Tratos Infantis
/
Comportamento Infantil
/
Desenvolvimento Infantil
/
Transtornos de Deficit da Atenção e do Comportamento Disruptivo
Tipo de estudo:
Prognostic_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Adult
/
Child
/
Female
/
Humans
/
Male
País/Região como assunto:
America do norte
Idioma:
En
Revista:
Psychol Med
Ano de publicação:
2012
Tipo de documento:
Article