[Standardised scoring of a multi-parametric 3-T MRI for a targeted MRI-guided prostate biopsy]. / Standardisierung des multiparametrischen 3-T-MRT zur zielgerichteten Biopsie der Prostata.
Urologe A
; 51(6): 848-56, 2012 Jun.
Article
em De
| MEDLINE
| ID: mdl-22476739
ABSTRACT
BACKGROUND:
The use of multi-parametric MRI and MRI-guided biopsy for the detection of prostate cancer is rapidly increasing. This is a pilot study to evaluate the consensus-based international MRI scoring system as decision criterion for targeted MRI-guided prostate biopsy. MATERIAL ANDMETHODS:
After a multi-parametric 3-T MRI (T2-weighted imaging, diffusion-weighted imaging, and dynamic contrast-enhanced MRI) in 23 consecutive patients a total of 47 lesions were scored according to a 5-point scale for each MRI sequence. A total score of ≥ 10 points was considered to be suspicious for prostate cancer. All 47 lesions were histologically assessed after MRI-guided biopsy.RESULTS:
At the cut-off score of 10 points, sensitivity, specificity, negative predictive value and positive predictive value of multi-parametric MRI were 94.1, 43.3, 92.9 and 48.5%, respectively.CONCLUSIONS:
A standardised scoring of lesions on multi-parametric MRI is feasible. The cut-off value leads to excellent values for sensitivity and negative predictive value. The values for specificity and positive predictive value are modest. Lesions with a total score <10 points are very unlikely to be malignant.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Próstata
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Biópsia por Agulha
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Imageamento por Ressonância Magnética
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Interpretação de Imagem Assistida por Computador
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Cirurgia Assistida por Computador
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Limite:
Adult
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Aged
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Aged80
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Humans
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Male
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Middle aged
Idioma:
De
Revista:
Urologe A
Ano de publicação:
2012
Tipo de documento:
Article