Lunatic fringe deficiency cooperates with the Met/Caveolin gene amplicon to induce basal-like breast cancer.

Xu, Keli; Usary, Jerry; Kousis, Philaretos C; Prat, Aleix; Wang, Dong-Yu; Adams, Jessica R; Wang, Wei; Loch, Amanda J; Deng, Tao; Zhao, Wei; Cardiff, Robert Darrell; Yoon, Keejung; Gaiano, Nicholas; Ling, Vicki; Beyene, Joseph; Zacksenhaus, Eldad; Gridley, Tom; Leong, Wey L; Guidos, Cynthia J; Perou, Charles M; Egan, Sean E

Xu, Keli; Usary, Jerry; Kousis, Philaretos C; Prat, Aleix; Wang, Dong-Yu; Adams, Jessica R; Wang, Wei; Loch, Amanda J; Deng, Tao; Zhao, Wei; Cardiff, Robert Darrell; Yoon, Keejung; Gaiano, Nicholas; Ling, Vicki; Beyene, Joseph; Zacksenhaus, Eldad; Gridley, Tom; Leong, Wey L; Guidos, Cynthia J; Perou, Charles M; Egan, Sean E.

Afiliação

Xu K; Program in Developmental and Stem Cell Biology, The Hospital for Sick Children, Toronto, ON, M5G 1L7, Canada.
Usary J; Lineberger Comprehensive Cancer Center, Departments of Genetics and Pathology, University of North Carolina, Chapel Hill, NC 27599, USA.
Kousis PC; Program in Developmental and Stem Cell Biology, The Hospital for Sick Children, Toronto, ON, M5G 1L7, Canada.
Prat A; Lineberger Comprehensive Cancer Center, Departments of Genetics and Pathology, University of North Carolina, Chapel Hill, NC 27599, USA.
Wang DY; The Campbell Family Cancer Research Institute and Surgical Oncology Princess Margaret Hospital, and the Department of General Surgery, University Health Network, Toronto, ON M5S 1A1, Canada.
Adams JR; Program in Developmental and Stem Cell Biology, The Hospital for Sick Children, Toronto, ON, M5G 1L7, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A1, Canada.
Wang W; Program in Developmental and Stem Cell Biology, The Hospital for Sick Children, Toronto, ON, M5G 1L7, Canada.
Loch AJ; Program in Developmental and Stem Cell Biology, The Hospital for Sick Children, Toronto, ON, M5G 1L7, Canada.
Deng T; Division of Cell and Molecular Biology, Toronto General Research Institute, University Health Network, Toronto, ON M5S 1A1, Canada.
Zhao W; Lineberger Comprehensive Cancer Center, Departments of Genetics and Pathology, University of North Carolina, Chapel Hill, NC 27599, USA.
Cardiff RD; Center for Comparative Medicine, University of California, Davis, CA 95616, USA.
Yoon K; Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Gaiano N; Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Ling V; Program in Developmental and Stem Cell Biology, The Hospital for Sick Children, Toronto, ON, M5G 1L7, Canada; Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, M5G 1L7, Canada.
Beyene J; Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, M5G 1L7, Canada.
Zacksenhaus E; Division of Cell and Molecular Biology, Toronto General Research Institute, University Health Network, Toronto, ON M5S 1A1, Canada.
Gridley T; Center for Molecular Medicine, Maine Medical Center Research Institute, 81 Research Drive, Scarborough, ME 04074, USA.
Leong WL; The Campbell Family Cancer Research Institute and Surgical Oncology Princess Margaret Hospital, and the Department of General Surgery, University Health Network, Toronto, ON M5S 1A1, Canada.
Guidos CJ; Program in Developmental and Stem Cell Biology, The Hospital for Sick Children, Toronto, ON, M5G 1L7, Canada; Department of Immunology, University of Toronto, Toronto, ON M5S 1A1, Canada.
Perou CM; Lineberger Comprehensive Cancer Center, Departments of Genetics and Pathology, University of North Carolina, Chapel Hill, NC 27599, USA.
Egan SE; Program in Developmental and Stem Cell Biology, The Hospital for Sick Children, Toronto, ON, M5G 1L7, Canada; The Campbell Family Cancer Research Institute and Surgical Oncology Princess Margaret Hospital, and the Department of General Surgery, University Health Network, Toronto, ON M5S 1A1, Canada.

Cancer Cell ; 21(5): 626-641, 2012 May 15.

Article em En | MEDLINE | ID: mdl-22624713

Assuntos

Neoplasias da Mama/enzimologia; Caveolinas/metabolismo; Transformação Celular Neoplásica/metabolismo; Glicosiltransferases/metabolismo; Glândulas Mamárias Animais/enzimologia; Neoplasias Mamárias Experimentais/enzimologia; Células-Tronco Neoplásicas/enzimologia; Proteínas Proto-Oncogênicas c-met/metabolismo; Animais; Neoplasias da Mama/genética; Neoplasias da Mama/patologia; Proteínas de Ligação ao Cálcio/metabolismo; Caveolinas/genética; Proliferação de Células; Transformação Celular Neoplásica/genética; Transformação Celular Neoplásica/patologia; Células Cultivadas; Claudinas/metabolismo; Bases de Dados Genéticas; Feminino; Perfilação da Expressão Gênica/métodos; Regulação da Expressão Gênica no Desenvolvimento; Regulação Neoplásica da Expressão Gênica; Glicosiltransferases/deficiência; Glicosiltransferases/genética; Humanos; Imuno-Histoquímica; Peptídeos e Proteínas de Sinalização Intercelular/metabolismo; Proteína Jagged-1; Glândulas Mamárias Animais/crescimento & desenvolvimento; Glândulas Mamárias Animais/patologia; Glândulas Mamárias Animais/transplante; Neoplasias Mamárias Experimentais/genética; Neoplasias Mamárias Experimentais/patologia; Proteínas de Membrana/metabolismo; Camundongos; Camundongos Knockout; Pessoa de Meia-Idade; Células-Tronco Neoplásicas/patologia; Células-Tronco Neoplásicas/transplante; Análise de Sequência com Séries de Oligonucleotídeos; Proteínas Proto-Oncogênicas c-met/genética; Receptor IGF Tipo 1/metabolismo; Receptores Notch/metabolismo; Proteínas Serrate-Jagged; Transdução de Sinais

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Neoplásicas / Neoplasias da Mama / Transformação Celular Neoplásica / Glicosiltransferases / Proteínas Proto-Oncogênicas c-met / Caveolinas / Glândulas Mamárias Animais / Neoplasias Mamárias Experimentais Idioma: En Revista: Cancer Cell Ano de publicação: 2012 Tipo de documento: Article

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