[The process of X inactivation in the mouse]. / Le modèle de l'inactivation du chromosome X chez la souris.
Med Sci (Paris)
; 28(5): 526-30, 2012 May.
Article
em Fr
| MEDLINE
| ID: mdl-22643007
ABSTRACT
X chromosome inactivation (XCI) is an excellent model for studying how epigenetic marks are initiated during early embryogenesis. XCI is an essential process that takes place in females, leading to dosage compensation between males and females. In mouse, it occurs in two waves the first one is paternally imprinted, during the preimplantation period and the second one occurs in a random fashion. We provide here an update of the main molecular steps and hypothesis underlining this complex process.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Inativação do Cromossomo X
/
Camundongos
Limite:
Animals
Idioma:
Fr
Revista:
Med Sci (Paris)
Ano de publicação:
2012
Tipo de documento:
Article