Superfamily 2 helicases.
Front Biosci (Landmark Ed)
; 17(6): 2070-88, 2012 06 01.
Article
em En
| MEDLINE
| ID: mdl-22652765
ABSTRACT
Superfamily 2 helicases are involved in all aspects of RNA metabolism, and many steps in DNA metabolism. This review focuses on the basic mechanistic, structural and biological properties of each of the families of helicases within superfamily 2. There are ten separate families of helicases within superfamily 2, each playing specific roles in nucleic acid metabolism. The mechanisms of action are diverse, as well as the effect on the nucleic acid. Some families translocate on single-stranded nucleic acid and unwind duplexes, some unwind double-stranded nucleic acids without translocation, and some translocate on double-stranded or single-stranded nucleic acids without unwinding.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
DNA Helicases
/
RNA Helicases
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Front Biosci (Landmark Ed)
Ano de publicação:
2012
Tipo de documento:
Article