In vivo optical spectroscopy monitoring in a new model of muscular compartment syndrome.
Br J Anaesth
; 109(4): 561-5, 2012 Oct.
Article
em En
| MEDLINE
| ID: mdl-22763805
ABSTRACT
BACKGROUND:
Muscular compartment syndrome (MCS) is a rare but serious postoperative complication. In vivo optical spectroscopy (INVOS) monitors continuously and non-invasively regional oxygen saturation (rSO(2)), and could predict the development of MCS.METHODS:
In 10 healthy volunteers, we inflated a tourniquet to the mean arterial pressure to produce slight venous congestion and arterial hypoperfusion. Comparisons were made between the relative reduction in rSO(2) with baseline (deltaINVOS) and the time to observe motor nerve block (with non-invasive electromyography). Neurological symptoms, pain, and invasive intracompartmental pressure (ICP) were assessed.RESULTS:
In the eight volunteers completing the protocol, we observed a profound motor nerve conduction block, immediately reversible. Baseline values were [mean (sd)] INVOS 73.3 (8.9)% and ICP 16.9 (8.6) mm Hg. At the time of the block, values were INVOS 46.4 (10.9)%, deltaINVOS 28.7 (10.6)%, and ICP 70.0 (5.5) mm Hg. The time to reach the block was 33.0 (10.9) min, and to a deltaINVOS>10% 27.4 (10.4) min. Receiver-operating characteristic curves demonstrated a similar accuracy of ICP and INVOS to predict the occurrence of the block. Twenty minutes with a deltaINVOS>10% or ICP>30 mm Hg were associated with a sensitivity and a specificity of 95% and 70%; or 91% and 65%, respectively.CONCLUSIONS:
We have developed a model of acute immediately reversible MCS. Monitoring using the INVOS technology is as accurate as measurement of ICP, and could be a useful tool to prevent development of intraoperative MCS.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Complicações Pós-Operatórias
/
Síndromes Compartimentais
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Monitorização Fisiológica
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Doenças Musculares
Tipo de estudo:
Prognostic_studies
Limite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Br J Anaesth
Ano de publicação:
2012
Tipo de documento:
Article