Metabolomic investigation of Mytilus galloprovincialis (Lamarck 1819) caged in aquatic environments.
Ecotoxicol Environ Saf
; 84: 139-46, 2012 Oct.
Article
em En
| MEDLINE
| ID: mdl-22818846
ABSTRACT
Environmental metabolomics was applied to assess the metabolic responses in transplanted mussels to environmental pollution. Specimens of Mytilus galloprovincialis, sedentary filter-feeders, were caged in anthropogenic-impacted and reference sites along the Augusta coastline (Sicily, Italy). Chemical analysis revealed increased levels of PAHs in the digestive gland of mussels from the industrial area compared with control, and marked morphological changes were also observed. Digestive gland metabolic profiles, obtained by 1H NMR spectroscopy and analyzed by multivariate statistics, showed changes in metabolites involved in energy metabolism. Specifically, changes in lactate and acetoacetate could indicate increased anaerobic fermentation and alteration in lipid metabolism, respectively, suggesting that the mussels transplanted to the contaminated field site were suffering from adverse environmental condition. The NMR-based environmental metabolomics applied in this study results thus in it being a useful and effective tool for assessing environmental influences on the health status of aquatic organisms.
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
2_ODS3
Base de dados:
MEDLINE
Assunto principal:
Poluentes Químicos da Água
/
Mytilus
/
Metabolômica
Aspecto:
Patient_preference
Limite:
Animals
País/Região como assunto:
Europa
Idioma:
En
Revista:
Ecotoxicol Environ Saf
Ano de publicação:
2012
Tipo de documento:
Article