[Colorectal cancer and canonical Wnt signalling pathway]. / Kolorektální karcinom a kanonická Wnt signalizace.
Cas Lek Cesk
; 151(7): 335-42, 2012.
Article
em Cs
| MEDLINE
| ID: mdl-22913786
ABSTRACT
Colorectal cancer is among the most frequent malignancies in the economically developed part of the world including the Czech Republic. From the molecular biological point of view, the development of colorectal cancer is in most cases linked to the pathologically activated canonical Wnt signalling pathway. The aim of this review is to present this intercellular signalling pathway, its role in the colorectal carcinogenesis and possible therapeutic implications according to our current knowledge.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Colorretais
/
Via de Sinalização Wnt
Limite:
Humans
Idioma:
Cs
Revista:
Cas Lek Cesk
Ano de publicação:
2012
Tipo de documento:
Article