Can high-resolution ultrasound avoid the sentinel lymph-node biopsy procedure in the staging process of patients with stage I-II cutaneous melanoma?
Ultraschall Med
; 33(7): E179-E185, 2012 Dec.
Article
em En
| MEDLINE
| ID: mdl-22923259
ABSTRACT
PURPOSE:
The objective of our study was to define the diagnostic accuracy of high-resolution ultrasound (US) in detecting nodal involvement before sentinel lymph node biopsy (SLNB) in patients with cutaneous melanoma, to define the sonographic criteria used to assess nodal metastases, and to establish if high-resolution US can directly select patients to radical lymphadenectomy, sparing selective lymphadenectomy. MATERIALS ANDMETHODS:
623 patients underwent high-resolution US of the regional lymph nodes, 24 hours prior being submitted to the sentinel lymph node biopsy procedure. The US findings were compared with histological findings.RESULTS:
In 14.7â% out of 122 excised lymph nodes, high-resolution US showed sonographic features consistent with malignant involvement before the surgical step.âUS scan sensitivity and specificity were 15 and 100â%, respectively, since positive and negative predictive values were 100 and 87â% respectively.CONCLUSION:
US is an effective modality in the presurgical detection of subclinical deposits within sentinel lymph nodes. However, preoperative staging work-up with high-resolution US cannot substitute the SLNB, mainly because of low sensitivity due to missing many micrometastases.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Cutâneas
/
Interpretação de Imagem Assistida por Computador
/
Aumento da Imagem
/
Ultrassonografia Doppler em Cores
/
Biópsia de Linfonodo Sentinela
/
Melanoma
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
En
Revista:
Ultraschall Med
Ano de publicação:
2012
Tipo de documento:
Article