Chemical sensitization and allergotoxicology.
Exp Suppl
; 101: 289-314, 2012.
Article
em En
| MEDLINE
| ID: mdl-22945573
ABSTRACT
Chemical sensitization remains an important environmental and occupational health issue. A wide range of substances have been shown to possess the ability to induce skin sensitization or respiratory sensitization. As a consequence, there is a need to have appropriate methods to identify sensitizing agents. Although a considerable investment has been made in exploring opportunities to develop methods for hazard identification and characterization, there are, as yet, no validated nonanimal methods available. A state of the art of the different in vitro approaches to identify contact and respiratory capacity of chemicals is covered in this chapter.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hipersensibilidade Respiratória
/
Alérgenos
/
Dermatite Alérgica de Contato
Limite:
Humans
Idioma:
En
Revista:
Exp Suppl
Ano de publicação:
2012
Tipo de documento:
Article