[A new immunoassay for estradiol on the Advia-Centaur (Siemens) system: analytical and clinical performances]. / Performances analytiques d'un nouveau dosage de l'estradiol pour l'Advia-Centaur (Siemens) : évaluation clinique dans le cadre de l'assistance médicale à la procréation.
Ann Biol Clin (Paris)
; 70(5): 581-9, 2012 Oct 01.
Article
em Fr
| MEDLINE
| ID: mdl-23047904
ABSTRACT
The objective of this study is to present results for measurement of estradiol (E(2)) in serum and control materials with a new automated assay (eE(2)) that could be used in random continuous access mode on the Siemens laboratories Advia-Centaur immunoassay analyzer. We evaluated the imprecision (within and between run), the linearity, the limit of detection, and the functional sensitivity. We have tested the assay for monitoring ovulation stimulation for in vitro fertilization and embryo transfer (IVF-ET) throughout the most frequent protocol utilized in our IVF centre (n = 247). Results are compared to those obtained by the E(2)6 assay, one other assay on the Advia-Centaur immunoassay analyzer (Siemens), routinely used in our hormonology department. The obtained results show that the new assay presents better analytical performances (precision, linearity, limits of detection and sensibility) than the previous technique.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Análise Química do Sangue
/
Estradiol
Tipo de estudo:
Diagnostic_studies
/
Evaluation_studies
/
Prognostic_studies
Limite:
Female
/
Humans
Idioma:
Fr
Revista:
Ann Biol Clin (Paris)
Ano de publicação:
2012
Tipo de documento:
Article