Novel technique for MR elastography of the prostate using a modified standard endorectal coil as actuator.
J Magn Reson Imaging
; 37(6): 1480-5, 2013 Jun.
Article
em En
| MEDLINE
| ID: mdl-23055397
ABSTRACT
PURPOSE:
To present a novel method for MR elastography (MRE) of the prostate at 3 Tesla using a modified endorectal imaging coil. MATERIALS ANDMETHODS:
A commercial endorectal coil was modified to dynamically generate mechanical stress (contraction and dilation) in a prostate phantom with embedded phantom "lesions" (6 mm diameter) and in a porcine model. Resulting tissue displacements were measured with a motion-sensitive EPI sequence at actuation frequencies of 50-200 Hz. Maps of shear modulus G were calculated from the measured phase-difference shear-wave patterns.RESULTS:
In the G maps of the phantom, "lesions" were easily discernible against the background. The average G values of regions of interest placed in the "lesion" (8.2 ± 1.9 kPa) were much higher than those in the background (3.6 ± 1.4 kPa) but systematically lower than values reported by the vendor (13.0 ± 1.0 and 6.7 ± 0.7 kPa, respectively). In the porcine model, shear waves could be generated and measured shear moduli were substantially different for muscle (7.1 ± 2.0 kPa), prostate (3.0 ± 1.4 kPa), and bulbourethral gland (5.6 ± 1.9 kPa).CONCLUSION:
An endorectal MRE concept is technically feasible. The presented technique will allow for simultaneous MRE and MRI acquisitions using a commercial base device with minor, MR-conditional modifications. The diagnostic value needs to be determined in further trials.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Próstata
/
Transdutores
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Imageamento por Ressonância Magnética
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Aumento da Imagem
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Técnicas de Imagem por Elasticidade
/
Magnetismo
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
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Male
Idioma:
En
Revista:
J Magn Reson Imaging
Ano de publicação:
2013
Tipo de documento:
Article