Variable-pitch rectangular cross-section radiofrequency coils for the nitrogen-14 nuclear quadrupole resonance investigation of sealed medicines packets.
Anal Chem
; 84(21): 8970-2, 2012 Nov 06.
Article
em En
| MEDLINE
| ID: mdl-23057555
ABSTRACT
The performance of rectangular radio frequency (RF) coils capable of being used to detect nuclear quadrupole resonance (NQR) signals from blister packs of medicines has been compared. The performance of a fixed-pitch RF coil was compared with that from two variable-pitch coils, one based on a design in the literature and the other optimized to obtain the most homogeneous RF field over the whole volume of the coil. It has been shown from (14)N NQR measurements with two medicines, the antibiotic ampicillin (as trihydrate) and the analgesic medicine Paracetamol, that the latter design gives NQR signal intensities almost independent of the distribution of the capsules or pills within the RF coil and is therefore more suitable for quantitative analysis.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ondas de Rádio
/
Espectroscopia de Ressonância Magnética
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Embalagem de Medicamentos
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Ampicilina
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Acetaminofen
Idioma:
En
Revista:
Anal Chem
Ano de publicação:
2012
Tipo de documento:
Article