Complete genome sequence of Newcastle disease virus mesogenic vaccine strain R2B from India.
J Virol
; 86(24): 13814-5, 2012 Dec.
Article
em En
| MEDLINE
| ID: mdl-23166233
ABSTRACT
Mesogenic vaccine strains of Newcastle disease virus (NDV) are widely used in many countries of Asia and Africa to control the Newcastle disease of poultry. In India, the mesogenic strain R2B was introduced in 1945; it protects adult chickens that have been preimmunized with a lentogenic vaccine virus and provides long-lasting immunity. In this article, we report the complete genome sequence of the hitherto unsequenced Indian vaccine virus strain R2B. The viral genome is 15,186 nucleotides in length and contains the polybasic amino acid motif in the fusion protein cleavage site, indicating that this vaccine strain has evolved from a virulent virus. Phylogenetic analysis of this mesogenic vaccine virus classified it with the viruses belonging to genotype III of the class cluster II of NDV.
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
1_ASSA2030
Base de dados:
MEDLINE
Assunto principal:
Vírus da Doença de Newcastle
/
Vacinas Virais
/
Genoma Viral
Limite:
Animals
País/Região como assunto:
Asia
Idioma:
En
Revista:
J Virol
Ano de publicação:
2012
Tipo de documento:
Article