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Synthesis, spectral, thermal and antibacterial investigations of mixed ligand complexes of thorium(IV) derived from 8-hydroxyquinoline and some amino acids.
Patil, Sunil S; Thakur, Ganesh A; Shaikh, Manzoor M.
Afiliação
  • Patil SS; Department of Chemistry, Changu Kana Thakur Arts, Commerce and Science College, Maharashtra, India. sunilpatil_247@rediffmail.com
Acta Pol Pharm ; 69(6): 1087-93, 2012.
Article em En | MEDLINE | ID: mdl-23285669
Mixed ligand Th(IV) complexes of the type [M(Q)(L)(NO3)2] x 2 H2O have been synthesized using 8-hydroxyquinoline (HQ) as a primary ligand and N- and/or O- donor amino acids (HL) such as L-lysine, L-aspartic acid and L-cysteine as secondary ligands. The metal complexes have been characterized on the basis of elemental analysis, electrical conductance, room temperature magnetic susceptibility measurements,spectral and thermal studies. The electrical conductance studies of the complexes in DMF in 10(-3) M concentration indicate their non-electrolytic nature. Room temperature magnetic susceptibility measurements revealed diamagnetic nature of the complexes. Electronic absorption spectra of the complexes show intra-ligand and charge transfer transitions, respectively. Bonding of the metal ion through N- and O- donor atoms of the ligands revealed by IR studies and the chemical environment of the protons is also confirmed by NMR studies. The thermal analysis data of the complexes indicate the presence of crystallized water molecules. The agar cup and tube dilution method have been used to study the antibacterial activity of the complexes against the pathogenic bacteria S. aureus, C. diphtheriae, S. typhi and E. coli.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxiquinolina / Compostos de Tório / Aminoácidos / Antibacterianos Idioma: En Revista: Acta Pol Pharm Ano de publicação: 2012 Tipo de documento: Article
Buscar no Google
Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxiquinolina / Compostos de Tório / Aminoácidos / Antibacterianos Idioma: En Revista: Acta Pol Pharm Ano de publicação: 2012 Tipo de documento: Article