Postoperative residual neuromuscular blockade is associated with impaired clinical recovery.
Anesth Analg
; 117(1): 133-41, 2013 Jul.
Article
em En
| MEDLINE
| ID: mdl-23337416
ABSTRACT
BACKGROUND:
In this investigation, we sought to determine the association between objective evidence of residual neuromuscular blockade (train-of-four [TOF] ratio <0.9) and the type, incidence, and severity of subjective symptoms of muscle weakness in the postanesthesia care unit (PACU).METHODS:
TOF ratios of 149 patients were quantified with acceleromyography on arrival to the PACU. Patients were stratified into 2 cohorts a TOF <0.9 group (n = 48) or a TOF ≥0.9 (control) group (n = 101). A standardized examination determined the presence or absence of 16 symptoms and 11 signs of muscle weakness on arrival to the PACU and 20, 40, and 60 minutes after admission.RESULTS:
The incidence of symptoms of muscle weakness was significantly higher in the TOF <0.9 group at all times (P < 0.001), as was the median (range) number of symptoms from PACU arrival (7 [3-6] TOF <0.9 group vs 2 [0-11] control group; difference 5, 99% confidence interval of the difference 4-6) until 60 minutes after admission (2 [0-12] TOF <0.9 group vs 0 [0-11] control group; difference 2, 99% confidence interval of the difference 1-2) (all P < 0.0001).CONCLUSION:
The incidence and severity of symptoms of muscle weakness were increased in the PACU in patients with a TOF <0.9.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Complicações Pós-Operatórias
/
Período de Recuperação da Anestesia
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Debilidade Muscular
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Bloqueio Neuromuscular
Tipo de estudo:
Clinical_trials
/
Risk_factors_studies
Limite:
Adult
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Aged
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Female
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Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Anesth Analg
Ano de publicação:
2013
Tipo de documento:
Article