Tandem reactions involving 1-silyl-3-boryl-2-alkenes. New access to (Z)-1-fluoro-1-alkenes, allyl fluorides, and diversely α-substituted allylboronates.
Org Lett
; 15(4): 906-9, 2013 Feb 15.
Article
em En
| MEDLINE
| ID: mdl-23391173
ABSTRACT
The reactions of 1-silyl-3-boryl-2-alkenes with various electrophilic reagents (Selectfluor, N-halosuccinimides, benzhydryl, and propargylic alcohols in the presence of a Lewis acid, N-alkoxycarbonyliminium ion) have been investigated as new routes to α-substituted allylboronates. Further functional transformations, including allylboration, Suzuki coupling, protodeboronation, and cycloisomerization, have been carried out to illustrate the synthetic potential of these γ-borylallylsilanes.
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Coleções:
01-internacional
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MEDLINE
Idioma:
En
Revista:
Org Lett
Ano de publicação:
2013
Tipo de documento:
Article