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The KMO allele encoding Arg452 is associated with psychotic features in bipolar disorder type 1, and with increased CSF KYNA level and reduced KMO expression.
Lavebratt, C; Olsson, S; Backlund, L; Frisén, L; Sellgren, C; Priebe, L; Nikamo, P; Träskman-Bendz, L; Cichon, S; Vawter, M P; Osby, U; Engberg, G; Landén, M; Erhardt, S; Schalling, M.
Afiliação
  • Lavebratt C; 1] Neurogenetics Unit, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden [2] Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden.
  • Olsson S; Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.
  • Backlund L; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
  • Frisén L; 1] Neurogenetics Unit, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden [2] Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden [3] Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
  • Sellgren C; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
  • Priebe L; 1] Department of Genomics, Life and Brain Center, University of Bonn, Bonn, Germany [2] Institute of Human Genetics, University of Bonn, Bonn, Germany.
  • Nikamo P; 1] Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden [2] Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.
  • Träskman-Bendz L; Department of Clinical Sciences, University Hospital, Lund, Sweden.
  • Cichon S; 1] Department of Genomics, Life and Brain Center, University of Bonn, Bonn, Germany [2] Institute of Human Genetics, University of Bonn, Bonn, Germany [3] Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organization of the Brain, Genomic Imaging, Research Center Juelich, Ju
  • Vawter MP; Functional Genomics Laboratory, Department of Psychiatry and Human Behavior, University of California Irvine School of Medicine, Irvine, CA, USA.
  • Osby U; 1] Neurogenetics Unit, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden [2] Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden [3] Department of Psychiatry, Tiohundra AB, Norrtälje, Sweden.
  • Engberg G; Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.
  • Landén M; 1] Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden [2] Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden.
  • Erhardt S; Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.
  • Schalling M; 1] Neurogenetics Unit, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden [2] Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden.
Mol Psychiatry ; 19(3): 334-41, 2014 Mar.
Article em En | MEDLINE | ID: mdl-23459468
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtornos Psicóticos / Transtorno Bipolar / Quinurenina 3-Mono-Oxigenase / Ácido Cinurênico Tipo de estudo: Diagnostic_studies / Observational_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Mol Psychiatry Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtornos Psicóticos / Transtorno Bipolar / Quinurenina 3-Mono-Oxigenase / Ácido Cinurênico Tipo de estudo: Diagnostic_studies / Observational_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Mol Psychiatry Ano de publicação: 2014 Tipo de documento: Article