[The significance of immunity disorders in the development of tumorous effects during the long-term action of tritium in mice]. / Znachenie narushenii immuniteta v razvitii opukholevykh éffektov pri dlitel'nom deistvii tritiia u myshei.
Radiobiologiia
; 30(2): 179-84, 1990.
Article
em Ru
| MEDLINE
| ID: mdl-2349376
In experiments with CBA mice it was shown that the long-term influence of tritium oxide administered with drinking water daily during 180 days (370 kBq.g-1 of body mass, cumulative dose 8.7 Gy, dose rate 4.5 cGy.day-1) causes the development of immunity deficiency 90 days after the onset of the administration that persists for up to 270 days. There is a 34% decrease in the average life of irradiated animals and an increase in the number of malignant neoplasms (postmortem examination was performed after natural death or killing on days 250, 350 and 450). There is a direct relationship between the occurrence of malignant neoplasms and the immunity deficiency.
Buscar no Google
Coleções:
01-internacional
Contexto em Saúde:
2_ODS3
/
6_ODS3_enfermedades_notrasmisibles
Base de dados:
MEDLINE
Assunto principal:
Trítio
/
Intoxicação por Água
/
Água
/
Neoplasias Induzidas por Radiação
Tipo de estudo:
Etiology_studies
Limite:
Animals
Idioma:
Ru
Revista:
Radiobiologiia
Ano de publicação:
1990
Tipo de documento:
Article