Steroidal glycosides from Reineckia carnea herba and their antitussive activity.
Planta Med
; 79(9): 788-91, 2013 Jun.
Article
em En
| MEDLINE
| ID: mdl-23670621
ABSTRACT
Two new steroidal glycosides, 1α,3α-dihydroxy-5ß-pregn-16-en-20-one 3-O-α-L-rhamnopyranoside (1) and 1ß,3ß,27-trihydroxycholest-16-en-22-one 1,3-di-O-α-L-rhamnoside (2), along with seven known steroidal glycosides (3-9), were isolated from Reineckia carnea herba. Their structures were determined by detailed analysis of their 1D- and 2D-NMR and MS spectra. Compound 9 was isolated for the first time from the Reineckia genus. Except for 8, compounds 2, 3, 4, 5, 6, 7, and 9 displayed clear in vitro antitussive activity.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Antitussígenos
/
Liliaceae
/
Glicosídeos
Limite:
Animals
Idioma:
En
Revista:
Planta Med
Ano de publicação:
2013
Tipo de documento:
Article