Relationship between activity of silica thin films and density of cells occupation.
J Biomed Mater Res A
; 102(6): 1707-14, 2014 Jun.
Article
em En
| MEDLINE
| ID: mdl-23775848
ABSTRACT
The SiO2 thin films (STFs) were deposited on the surfaces of stainless steel tapes and their activity was particularly investigated from the aspect of the number density of hydroxyl groups on their surfaces. The calculation procedure of density of active OH groups includes determination of average length of silica chains that constitute silica sol particles with almost uniform size, on the base of thermogravimetric analysis. The size of SiO2 particles is analyzed by transmission electron microscopy and dynamic light scattering method. Fibroblast (L929) cell densities on the surfaces of these films were investigated using phase contrast microcopy. It was shown that there is a relationship between OH group densities and density of attached cells. Besides, the cytotoxicity effect was studied and compared for various thermally treated STFs.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Dióxido de Silício
/
Materiais Revestidos Biocompatíveis
/
Fibroblastos
Aspecto:
Determinantes_sociais_saude
Limite:
Animals
Idioma:
En
Revista:
J Biomed Mater Res A
Ano de publicação:
2014
Tipo de documento:
Article