Effect of eicosapentaenoic acid agent on aggravated hypertriglyceridemia during pregnancy.
J Obstet Gynaecol Res
; 39(11): 1541-4, 2013 Nov.
Article
em En
| MEDLINE
| ID: mdl-23855742
ABSTRACT
Aggravated hypertriglyceridemia with a serum triglyceride of more than 1000 mg/dL is a risk of acute pancreatitis during pregnancy. However, there have been few reports on the administration of an eicosapentaenoic acid (EPA) agent for aggravated hypertriglyceridemia during pregnancy. A 29-year-old multiparous Japanese woman was transferred to our hospital at 29 + 0 weeks of gestation due to hypertriglyceridemia of 898 mg/dL. Because diet control was not enough, we decided to use an EPA agent, resulting in a reduction in triglyceride levels to 550 mg/dL. A male infant, weighing 2667 g, was born at 37 + 2 weeks transabdominally, and was complicated with respiratory distress syndrome. The final diagnosis was type III hyperlipoproteinemia with the apolipoprotein E3/2 phenotype and a broad ß-migrating lipoprotein on polyacrylamide gel electrophoresis of serum lipoproteins. In conclusion, an EPA agent may be a possible therapeutic approach for aggravated hypertriglyceridemia during pregnancy, although it may increase a risk of respiratory distress syndrome.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Complicações na Gravidez
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Hipertrigliceridemia
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Ácido Eicosapentaenoico
Limite:
Adult
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Female
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Humans
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Pregnancy
Idioma:
En
Revista:
J Obstet Gynaecol Res
Ano de publicação:
2013
Tipo de documento:
Article