Efficient metal-free synthesis of various pyrido[2',1':2,3]imidazo- [4,5-b]quinolines.

Arnould, Mathieu; Hiebel, Marie-Aude; Massip, Stéphane; Léger, Jean Michel; Jarry, Christian; Berteina-Raboin, Sabine; Guillaumet, Gérald

Arnould, Mathieu; Hiebel, Marie-Aude; Massip, Stéphane; Léger, Jean Michel; Jarry, Christian; Berteina-Raboin, Sabine; Guillaumet, Gérald.

Afiliação

Arnould M; Institut de Chimie Organique et Analytique (ICOA), Université d'Orléans, UMR-CNRS 7311, BP 6759, rue de Chartres, 45067 Orléans cedex 2 (France), Fax: (+33) 2-38-41-72-81.

Chemistry ; 19(37): 12249-53, 2013 Sep 09.

Article em En | MEDLINE | ID: mdl-23955568

ABSTRACT

ABSTRACT

Dancing with diversity The synthesis of diverse pyrido[2',1'2,3]imidazo[4,5-b]quinolines bearing several substitution patterns was developed based on combining a multicomponent reaction (Groebke-Blackburn-Bienaymé reaction) with an original cyclization as a secondary transformation (see scheme; DBU = 1,8-diazabicyclo[5.4.0]undec-7-ene).

Assuntos

Compostos Bicíclicos Heterocíclicos com Pontes/química; Compostos Bicíclicos Heterocíclicos com Pontes/síntese química; Metais/química; Quinolinas/química; Quinolinas/síntese química; Ciclização

Palavras-chave

Groebke-Blackburn-Bienaymé reaction; aromatic cyclization; cyclization; diversity-oriented synthesis; multicomponent reactions

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinolinas / Compostos Bicíclicos Heterocíclicos com Pontes / Metais Idioma: En Revista: Chemistry Ano de publicação: 2013 Tipo de documento: Article

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