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RGS6 suppresses Ras-induced cellular transformation by facilitating Tip60-mediated Dnmt1 degradation and promoting apoptosis.
Huang, J; Stewart, A; Maity, B; Hagen, J; Fagan, R L; Yang, J; Quelle, D E; Brenner, C; Fisher, R A.
Afiliação
  • Huang J; Department of Pharmacology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
  • Stewart A; Department of Pharmacology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
  • Maity B; Department of Pharmacology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
  • Hagen J; Department of Pharmacology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
  • Fagan RL; Department of Biochemistry, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
  • Yang J; Department of Pharmacology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
  • Quelle DE; Department of Pharmacology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
  • Brenner C; Department of Biochemistry, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
  • Fisher RA; Department of Pharmacology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Oncogene ; 33(27): 3604-11, 2014 Jul 03.
Article em En | MEDLINE | ID: mdl-23995786

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transativadores / Transformação Celular Neoplásica / Proteínas Proto-Oncogênicas p21(ras) / Apoptose / Proteínas RGS / DNA (Citosina-5-)-Metiltransferases / Histona Acetiltransferases / Proteólise Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Oncogene Ano de publicação: 2014 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transativadores / Transformação Celular Neoplásica / Proteínas Proto-Oncogênicas p21(ras) / Apoptose / Proteínas RGS / DNA (Citosina-5-)-Metiltransferases / Histona Acetiltransferases / Proteólise Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Oncogene Ano de publicação: 2014 Tipo de documento: Article