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Somatic mutations in MAP3K5 attenuate its proapoptotic function in melanoma through increased binding to thioredoxin.
Prickett, Todd D; Zerlanko, Brad; Gartner, Jared J; Parker, Stephen C J; Dutton-Regester, Ken; Lin, Jimmy C; Teer, Jamie K; Wei, Xiaomu; Jiang, Jiji; Chen, Guo; Davies, Michael A; Gershenwald, Jeffrey E; Robinson, William; Robinson, Steven; Hayward, Nicholas K; Rosenberg, Steven A; Margulies, Elliott H; Samuels, Yardena.
Afiliação
  • Prickett TD; The Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA.
  • Zerlanko B; The Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA.
  • Gartner JJ; The Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA.
  • Parker SCJ; The Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA.
  • Dutton-Regester K; Oncogenomics Laboratory, QIMR Berghofer Medical Research Institute, Herston, Brisbane, Queensland, Australia.
  • Lin JC; Division of Laboratory and Genomic Medicine, Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri, USA.
  • Teer JK; Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA.
  • Wei X; The Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA.
  • Jiang J; The Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA.
  • Nisc Comparative Sequencing Program; NIH Intramural Sequencing Center, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA.
  • Chen G; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA; Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Davies MA; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA; Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Gershenwald JE; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Robinson W; Division of Medical Oncology, University of Colorado School of Medicine, Aurora, Colorado, USA.
  • Robinson S; Division of Medical Oncology, University of Colorado School of Medicine, Aurora, Colorado, USA.
  • Hayward NK; Oncogenomics Laboratory, QIMR Berghofer Medical Research Institute, Herston, Brisbane, Queensland, Australia.
  • Rosenberg SA; The Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
  • Margulies EH; Genome Informatics Section, Genome Technology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA.
  • Samuels Y; The Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA. Electronic address: Yardena.samuels@weizmann.ac.il.
J Invest Dermatol ; 134(2): 452-460, 2014 Feb.
Article em En | MEDLINE | ID: mdl-24008424

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Tiorredoxinas / MAP Quinase Quinase Quinase 5 / Melanoma Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Revista: J Invest Dermatol Ano de publicação: 2014 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Tiorredoxinas / MAP Quinase Quinase Quinase 5 / Melanoma Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Revista: J Invest Dermatol Ano de publicação: 2014 Tipo de documento: Article