Acne is an inflammatory disease and alterations of sebum composition initiate acne lesions.
J Eur Acad Dermatol Venereol
; 28(5): 527-32, 2014 May.
Article
em En
| MEDLINE
| ID: mdl-24134468
ABSTRACT
Hyperseborrhoea has been considered as a major aetiopathogenetic factor of acne. However, changes in sebaceous gland activity not only correlate with seborrhoea but also with alterations in sebum fatty acid composition. Current findings indicate that sebum lipid fractions with proinflammatory properties and inflammatory tissue cascades are associated in the process of the development of acne lesions. The oxidant/antioxidant ratio of the skin surface lipids and alterations of lipid composition are the main players in the induction of acne inflammation. Nutrition may influence the development of seborrhoea, the fractions of sebum lipids and acne. Acne is an inflammatory disease probably triggered, among others, by proinflammatory sebum lipid fractions.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Sebo
/
Acne Vulgar
/
Inflamação
Limite:
Humans
Idioma:
En
Revista:
J Eur Acad Dermatol Venereol
Ano de publicação:
2014
Tipo de documento:
Article