HRG-1 enhances cancer cell invasive potential and couples glucose metabolism to cytosolic/extracellular pH gradient regulation by the vacuolar-H(+) ATPase.

Fogarty, F M; O'Keeffe, J; Zhadanov, A; Papkovsky, D; Ayllon, V; O'Connor, R

Fogarty, F M; O'Keeffe, J; Zhadanov, A; Papkovsky, D; Ayllon, V; O'Connor, R.

Afiliação

Fogarty FM; Cell Biology Laboratory, University College Cork, BioSciences Institute, College Road, Cork, Ireland.
O'Keeffe J; Cell Biology Laboratory, University College Cork, BioSciences Institute, College Road, Cork, Ireland.
Zhadanov A; Laboratory of Biophysics and Bioanalysis, Department of Biochemistry, University College Cork, BioSciences Institute, College Road, Cork, Ireland.
Papkovsky D; Laboratory of Biophysics and Bioanalysis, Department of Biochemistry, University College Cork, BioSciences Institute, College Road, Cork, Ireland.
Ayllon V; Cell Biology Laboratory, University College Cork, BioSciences Institute, College Road, Cork, Ireland.
O'Connor R; Cell Biology Laboratory, University College Cork, BioSciences Institute, College Road, Cork, Ireland.

Oncogene ; 33(38): 4653-63, 2014 Sep 18.

Article em En | MEDLINE | ID: mdl-24141772

Assuntos

Glucose/metabolismo; Hemeproteínas/fisiologia; ATPases Vacuolares Próton-Translocadoras/fisiologia; Membrana Celular/metabolismo; Citosol/metabolismo; Líquido Extracelular/metabolismo; Transportador de Glucose Tipo 1/metabolismo; Humanos; Concentração de Íons de Hidrogênio; Ácido Láctico/metabolismo; Células MCF-7; Metaloproteinase 2 da Matriz/metabolismo; Metaloproteinase 9 da Matriz/metabolismo; Invasividade Neoplásica; Transporte Proteico

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: ATPases Vacuolares Próton-Translocadoras / Glucose / Hemeproteínas Limite: Humans Idioma: En Revista: Oncogene Ano de publicação: 2014 Tipo de documento: Article

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