Usefulness of continuous blood glucose monitoring and control for patients undergoing liver transplantation.
J Med Invest
; 60(3-4): 205-12, 2013.
Article
em En
| MEDLINE
| ID: mdl-24190037
ABSTRACT
BACKGROUND:
The purpose of this study was to evaluate the usefulness of the closed-loop system (STG-22; Nikkiso, Tokyo, Japan), a type of artificial endocrine pancreas for the continuous monitoring and control of intraoperative blood glucose in patients undergoing liver transplantation.METHODS:
Sixteen patients undergoing living-donor liver transplantation were enrolled in this study. Glucose levels were controlled with either a manual injection of insulin based on a commonly used sliding scale (manual insulin group, n=8) or a programmed infusion of insulin determined by the control algorithm of the artificial endocrine pancreas (programmed insulin group, n=8). The target glucose level range was set at 80-150 mg/dl.RESULTS:
The mean and SD of blood glucose concentration during surgery (Glu-Ave and Glu-SD, respectively) for the programmed insulin group were lower than for the manual insulin group. The coefficient of variability (Glu-CV=Glu-SD×100 /Glu-Ave) for the programmed insulin group was also lower than for the manual insulin group (20.1±4.9% vs. 26.9±6.1%; mean±SD). No hypoglycemia was detected in either group.CONCLUSION:
The STG-22 closed-loop system is effective for maintaining strict blood glucose control during liver transplantation with minimal variability in blood glucose concentration.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Glicemia
/
Sistemas de Infusão de Insulina
/
Transplante de Fígado
Tipo de estudo:
Evaluation_studies
Limite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
J Med Invest
Ano de publicação:
2013
Tipo de documento:
Article