Effect of wound infiltration with bupivacaine on pulmonary function after elective lower abdominal operations.
Afr Health Sci
; 13(3): 756-61, 2013 Sep.
Article
em En
| MEDLINE
| ID: mdl-24250318
ABSTRACT
BACKGROUND:
Subcutaneous or intrafascial wound infiltration of local anaesthetic with systemic opioids has been shown to enhance patient comfort with improved analgesia and reduced opioid requirements.OBJECTIVE:
To demonstrate improved pulmonary function when postoperative analgesia was provided by combined bupivacaine wound infiltration and systemic opioid.METHODS:
In a prospective, randomized, placebo-controlled study, 46 patients (23 per group) scheduled for elective gynaecological surgery under general anaesthesia had subcutaneous and intrafascial wound infiltration of 40 ml, 0.25% bupivacaine (study patients) or 40 ml 0.9% saline (control) just before the end of surgery. Forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1) and peak expiratory flow rate (PEFR) were done before surgery and at 6, 12 and 24 hours postoperatively. Student's T and chi-square tests were used for tests of significance set at P < 0.05. Postoperative analgesia was provided with intramuscular morphine 0.15 mg/kg 4 hourly and 10mg/kg of intravenous paracetamol as rescue analgesia.RESULTS:
PEFR, FVC and FEV1 were reduced in both the control and study groups but the reduction was greater in the control group.CONCLUSION:
Bupivacaine wound infiltration produced statistically significant elevations in pulmonary function tests results at all assessment periods.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Bupivacaína
/
Pico do Fluxo Expiratório
/
Volume Expiratório Forçado
/
Procedimentos Cirúrgicos Eletivos
/
Abdome
/
Anestésicos Locais
Tipo de estudo:
Clinical_trials
/
Observational_studies
/
Risk_factors_studies
Limite:
Adult
/
Humans
/
Middle aged
País/Região como assunto:
Africa
Idioma:
En
Revista:
Afr Health Sci
Ano de publicação:
2013
Tipo de documento:
Article