PACAP promotes neuron survival in early experimental diabetic retinopathy.

Szabadfi, Krisztina; Szabo, Aliz; Kiss, Peter; Reglodi, Dora; Setalo, Gyorgy; Kovacs, Krisztina; Tamas, Andrea; Toth, Gabor; Gabriel, Robert

Szabadfi, Krisztina; Szabo, Aliz; Kiss, Peter; Reglodi, Dora; Setalo, Gyorgy; Kovacs, Krisztina; Tamas, Andrea; Toth, Gabor; Gabriel, Robert.

Afiliação

Szabadfi K; Department of Experimental Zoology and Neurobiology, University of Pecs, Pecs, Hungary. Electronic address: kriszta.szabadfi@gmail.com.
Szabo A; Department of Biochemistry and Medical Chemistry, University of Pecs, Pecs, Hungary.
Kiss P; Department of Anatomy, PTE-MTA Lendulet PACAP Research Team, University of Pecs, Pecs, Hungary.
Reglodi D; Department of Anatomy, PTE-MTA Lendulet PACAP Research Team, University of Pecs, Pecs, Hungary.
Setalo G; Department of Medical Biology, University of Pecs, Pecs, Hungary.
Kovacs K; Department of Biochemistry and Medical Chemistry, University of Pecs, Pecs, Hungary.
Tamas A; Department of Anatomy, PTE-MTA Lendulet PACAP Research Team, University of Pecs, Pecs, Hungary.
Toth G; Department of Medical Chemistry, University of Szeged, Szeged, Hungary.
Gabriel R; Department of Experimental Zoology and Neurobiology, University of Pecs, Pecs, Hungary; Janos Szentagothai Research Center, Pecs, Hungary.

Neurochem Int ; 64: 84-91, 2014 Jan.

Article em En | MEDLINE | ID: mdl-24262293

Assuntos

Apoptose/efeitos dos fármacos; Retinopatia Diabética/metabolismo; Neurônios/efeitos dos fármacos; Polipeptídeo Hipofisário Ativador de Adenilato Ciclase/farmacologia; Animais; Retinopatia Diabética/tratamento farmacológico; Retinopatia Diabética/patologia; Modelos Animais de Doenças; Masculino; Neurônios/metabolismo; Neurônios/patologia; Ratos; Ratos Wistar; Retina/efeitos dos fármacos; Retina/metabolismo; Retina/patologia; Estreptozocina

Palavras-chave

Anti-apoptotic factors; Caspases; Diabetic retinopathy; ER; ERKs; GAPDH; GCL; GSK3ß; INL; IPL; MAPKs; ONL; OPL; PAC1-R; PACAP; PACAP type 1 receptor; PKA; PKC; TH; TUNEL; VIP; endoplasmatic reticulum; extracellular signal-regulated kinases; ganglion cell layer; glyceraldehyde 3-phosphate dehydrogenase; glycogen synthase kinase 3 beta; inner nuclear layer; inner plexiform layer; mitogen activated protein kinases; outer nuclear layer; outer plexiform layer; pituitary adenylate cyclase activating polypeptide; protein kinase A; protein kinase C; terminal transferase dUTP nick end labeling; tyrosine hydroxylase; vasoactive intestinal peptide

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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Apoptose / Retinopatia Diabética / Polipeptídeo Hipofisário Ativador de Adenilato Ciclase / Neurônios Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Neurochem Int Ano de publicação: 2014 Tipo de documento: Article

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