Copper-catalyzed oxidative three-component synthesis of N, N',Nâ³-trisubstituted guanidines.
Org Lett
; 15(24): 6124-7, 2013 Dec 20.
Article
em En
| MEDLINE
| ID: mdl-24266768
ABSTRACT
A copper-catalyzed three-component synthesis of trisubstituted N-aryl guanidines involving cyanamides, arylboronic acids, and amines has been developed. This operationally simple oxidative process, which is performed in the presence of K2CO3, a catalytic amount of CuCl2·2H2O, bipyridine, and oxygen (1 atm), allows the rapid assembly of N,N',Nâ³-trisubstituted aryl guanidines.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cobre
/
Guanidinas
Idioma:
En
Revista:
Org Lett
Ano de publicação:
2013
Tipo de documento:
Article