Inhibitory effects of beta-amyloid on the nicotinic receptors which stimulate glutamate release in rat hippocampus: the glial contribution.

Salamone, Alessia; Mura, Elisa; Zappettini, Stefania; Grilli, Massimo; Olivero, Guendalina; Preda, Stefania; Govoni, Stefano; Marchi, Mario

Salamone, Alessia; Mura, Elisa; Zappettini, Stefania; Grilli, Massimo; Olivero, Guendalina; Preda, Stefania; Govoni, Stefano; Marchi, Mario.

Afiliação

Salamone A; Section of Pharmacology and Toxicology, Department of Pharmacy, University of Genoa, Genoa, Italy.
Mura E; Department of Drug Sciences, Centre of Excellence in Applied Biology, University of Pavia, Pavia, Italy.
Zappettini S; Section of Pharmacology and Toxicology, Department of Pharmacy, University of Genoa, Genoa, Italy.
Grilli M; Section of Pharmacology and Toxicology, Department of Pharmacy, University of Genoa, Genoa, Italy.
Olivero G; Section of Pharmacology and Toxicology, Department of Pharmacy, University of Genoa, Genoa, Italy.
Preda S; Department of Drug Sciences, Centre of Excellence in Applied Biology, University of Pavia, Pavia, Italy.
Govoni S; Department of Drug Sciences, Centre of Excellence in Applied Biology, University of Pavia, Pavia, Italy.
Marchi M; Section of Pharmacology and Toxicology, Department of Pharmacy, University of Genoa, Genoa, Italy; Center of Excellence for Biomedical Research, University of Genoa, Italy. Electronic address: marchi@pharmatox.unige.it.

Eur J Pharmacol ; 723: 314-21, 2014 Jan 15.

Article em En | MEDLINE | ID: mdl-24275353

Assuntos

Peptídeos beta-Amiloides/farmacologia; Ácido Glutâmico/metabolismo; Hipocampo/efeitos dos fármacos; Antagonistas Nicotínicos/farmacologia; Fragmentos de Peptídeos/farmacologia; Receptor Nicotínico de Acetilcolina alfa7/antagonistas & inibidores; Animais; Ácido Aspártico/metabolismo; Azetidinas/farmacologia; Compostos Bicíclicos Heterocíclicos com Pontes/farmacologia; Colina/farmacologia; Hipocampo/metabolismo; Masculino; Nicotina/farmacologia; Agonistas Nicotínicos/farmacologia; Piridinas/farmacologia; Quinuclidinas/farmacologia; Ratos; Ratos Wistar; Receptores Nicotínicos/metabolismo; Receptor Nicotínico de Acetilcolina alfa7/metabolismo; Ácido gama-Aminobutírico/metabolismo

Palavras-chave

Aminoacid release; Isolated nerve endings; Microdialysis; α4ß2 Nicotinic receptors; α7 Nicotinic receptors; ß-Amyloid

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fragmentos de Peptídeos / Peptídeos beta-Amiloides / Antagonistas Nicotínicos / Ácido Glutâmico / Receptor Nicotínico de Acetilcolina alfa7 / Hipocampo Limite: Animals Idioma: En Revista: Eur J Pharmacol Ano de publicação: 2014 Tipo de documento: Article

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