PPP1R1B-STARD3 chimeric fusion transcript in human gastric cancer promotes tumorigenesis through activation of PI3K/AKT signaling.

Yun, S M; Yoon, K; Lee, S; Kim, E; Kong, S-H; Choe, J; Kang, J M; Han, T-S; Kim, P; Choi, Y; Jho, S; Yoo, H; Bhak, J; Yang, H-K; Kim, S-J

Yun, S M; Yoon, K; Lee, S; Kim, E; Kong, S-H; Choe, J; Kang, J M; Han, T-S; Kim, P; Choi, Y; Jho, S; Yoo, H; Bhak, J; Yang, H-K; Kim, S-J.

Afiliação

Yun SM; 1] CHA Cancer Institute, CHA University, Seoul, Korea [2] Department of Biomedical Science, College of Life Science, CHA University, 605 Yeoksam-dong, Gangnam-gu, Seoul, Korea.
Yoon K; CHA Cancer Institute, CHA University, Seoul, Korea.
Lee S; 1] Personal Genomics Institute, Genome Research Foundation, Suwon, Korea [2] TheragenEtex Bio Institute, TheragenEtex Inc., Suwon, Korea.
Kim E; CHA Cancer Institute, CHA University, Seoul, Korea.
Kong SH; 1] Cancer Research Institute, Seoul National University, Seoul, Korea [2] Department of Surgery, Seoul National University College of Medicine, Seoul, Korea.
Choe J; CHA Cancer Institute, CHA University, Seoul, Korea.
Kang JM; CHA Cancer Institute, CHA University, Seoul, Korea.
Han TS; Cancer Research Institute, Seoul National University, Seoul, Korea.
Kim P; CHA Cancer Institute, CHA University, Seoul, Korea.
Choi Y; CHA Cancer Institute, CHA University, Seoul, Korea.
Jho S; Personal Genomics Institute, Genome Research Foundation, Suwon, Korea.
Yoo H; CHA Cancer Institute, CHA University, Seoul, Korea.
Bhak J; 1] Personal Genomics Institute, Genome Research Foundation, Suwon, Korea [2] TheragenEtex Bio Institute, TheragenEtex Inc., Suwon, Korea.
Yang HK; 1] Cancer Research Institute, Seoul National University, Seoul, Korea [2] Department of Surgery, Seoul National University College of Medicine, Seoul, Korea.
Kim SJ; 1] CHA Cancer Institute, CHA University, Seoul, Korea [2] Department of Biomedical Science, College of Life Science, CHA University, 605 Yeoksam-dong, Gangnam-gu, Seoul, Korea.

Oncogene ; 33(46): 5341-7, 2014 Nov 13.

Article em En | MEDLINE | ID: mdl-24276243

Assuntos

Proteínas de Transporte/genética; Fosfoproteína 32 Regulada por cAMP e Dopamina/genética; Proteínas de Membrana/genética; Fosfatidilinositol 3-Quinases/metabolismo; Proteínas Proto-Oncogênicas c-akt/metabolismo; Neoplasias Gástricas/genética; Adulto; Idoso; Idoso de 80 Anos ou mais; Animais; Western Blotting; Carcinogênese/genética; Carcinogênese/metabolismo; Linhagem Celular Tumoral; Cromonas/farmacologia; Inibidores Enzimáticos/farmacologia; Feminino; Humanos; Masculino; Camundongos Nus; Pessoa de Meia-Idade; Morfolinas/farmacologia; Proteínas de Fusão Oncogênica/genética; Inibidores de Fosfoinositídeo-3 Quinase; Fosforilação/efeitos dos fármacos; Reação em Cadeia da Polimerase Via Transcriptase Reversa; Transdução de Sinais/efeitos dos fármacos; Neoplasias Gástricas/metabolismo; Neoplasias Gástricas/patologia; Transplante Heterólogo; Carga Tumoral/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas / Proteínas de Transporte / Fosfatidilinositol 3-Quinases / Proteínas Proto-Oncogênicas c-akt / Fosfoproteína 32 Regulada por cAMP e Dopamina / Proteínas de Membrana Tipo de estudo: Prognostic_studies Limite: Adult / Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Oncogene Ano de publicação: 2014 Tipo de documento: Article

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