Temozolomide-related acute lymphoblastic leukemia with translocation (4;11)(q21;q23) in a glioblastoma patient.
J Clin Neurosci
; 21(4): 701-4, 2014 Apr.
Article
em En
| MEDLINE
| ID: mdl-24291476
Temozolomide (TMZ), an alkylating agent, is widely used for treating high-grade gliomas. TMZ has been reported to cause secondary myelodysplastic syndrome and acute myeloid leukemia. However, TMZ-related acute lymphoblastic leukemia is rare. Here we describe a 54-year-old woman with glioblastoma multiforme, who developed precursor-B acute lymphoblastic leukemia with translocation (4;11)(q21;q23) after 15 months of TMZ treatment.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Encefálicas
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Glioblastoma
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Antineoplásicos Alquilantes
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Dacarbazina
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Leucemia-Linfoma Linfoblástico de Células Precursoras
Limite:
Female
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Humans
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Middle aged
Idioma:
En
Revista:
J Clin Neurosci
Ano de publicação:
2014
Tipo de documento:
Article