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Ibrutinib as initial therapy for elderly patients with chronic lymphocytic leukaemia or small lymphocytic lymphoma: an open-label, multicentre, phase 1b/2 trial.
O'Brien, Susan; Furman, Richard R; Coutre, Steven E; Sharman, Jeff P; Burger, Jan A; Blum, Kristie A; Grant, Barbara; Richards, Donald A; Coleman, Morton; Wierda, William G; Jones, Jeffrey A; Zhao, Weiqiang; Heerema, Nyla A; Johnson, Amy J; Izumi, Raquel; Hamdy, Ahmed; Chang, Betty Y; Graef, Thorsten; Clow, Fong; Buggy, Joseph J; James, Danelle F; Byrd, John C.
Afiliação
  • O'Brien S; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address: sobrien@mdanderson.org.
  • Furman RR; Department of Medicine, Division of Hematology-Oncology, Weill Cornell Medical College, New York, NY, USA.
  • Coutre SE; Division of Hematology and Stanford Cancer Center, Stanford University School of Medicine, Stanford, CA, USA.
  • Sharman JP; Willamette Valley Cancer Institute and Research Center/US Oncology Research, Springfield, OR, USA.
  • Burger JA; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Blum KA; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA.
  • Grant B; Vermont Cancer Center, University of Vermont, VT, USA.
  • Richards DA; Texas Oncology, US Oncology Research, Tyler, TX, USA.
  • Coleman M; Department of Medicine, Division of Hematology-Oncology, Weill Cornell Medical College, New York, NY, USA.
  • Wierda WG; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Jones JA; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA.
  • Zhao W; Department of Pathology, The Ohio State University, Columbus, OH, USA.
  • Heerema NA; Department of Pathology, The Ohio State University, Columbus, OH, USA.
  • Johnson AJ; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA.
  • Izumi R; Pharmacyclics, Sunnyvale, CA, USA.
  • Hamdy A; Pharmacyclics, Sunnyvale, CA, USA.
  • Chang BY; Pharmacyclics, Sunnyvale, CA, USA.
  • Graef T; Pharmacyclics, Sunnyvale, CA, USA.
  • Clow F; Pharmacyclics, Sunnyvale, CA, USA.
  • Buggy JJ; Pharmacyclics, Sunnyvale, CA, USA.
  • James DF; Pharmacyclics, Sunnyvale, CA, USA.
  • Byrd JC; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA.
Lancet Oncol ; 15(1): 48-58, 2014 Jan.
Article em En | MEDLINE | ID: mdl-24332241

Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: Pirazóis / Pirimidinas / Proteínas Tirosina Quinases / Leucemia Linfocítica Crônica de Células B / Inibidores de Proteínas Quinases Tipo de estudo: Clinical_trials Limite: Aged / Aged80 / Female / Humans / Male Idioma: En Revista: Lancet Oncol Ano de publicação: 2014 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: Pirazóis / Pirimidinas / Proteínas Tirosina Quinases / Leucemia Linfocítica Crônica de Células B / Inibidores de Proteínas Quinases Tipo de estudo: Clinical_trials Limite: Aged / Aged80 / Female / Humans / Male Idioma: En Revista: Lancet Oncol Ano de publicação: 2014 Tipo de documento: Article