Maternal-fetal metabolic gene-gene interactions and risk of neural tube defects.

Lupo, Philip J; Mitchell, Laura E; Canfield, Mark A; Shaw, Gary M; Olshan, Andrew F; Finnell, Richard H; Zhu, Huiping

Lupo, Philip J; Mitchell, Laura E; Canfield, Mark A; Shaw, Gary M; Olshan, Andrew F; Finnell, Richard H; Zhu, Huiping.

Afiliação

Lupo PJ; Department of Pediatrics, Section of Hematology-Oncology, Baylor College of Medicine, Houston, TX, USA.
Mitchell LE; Human Genetics Center, Division of Epidemiology, Human Genetics and Environmental Sciences, University of Texas School of Public Health, Houston, TX, USA.
Canfield MA; Texas Department of State Health Services, Austin, TX, USA.
Shaw GM; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA.
Olshan AF; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA.
Finnell RH; Dell Pediatric Research Institute, Department of Nutritional Sciences, University of Texas at Austin, Austin, TX, USA.
Zhu H; Dell Pediatric Research Institute, Department of Nutritional Sciences, University of Texas at Austin, Austin, TX, USA. Electronic address: hzhu@austin.utexas.edu.

Mol Genet Metab ; 111(1): 46-51, 2014 Jan.

Article em En | MEDLINE | ID: mdl-24332798

Assuntos

Predisposição Genética para Doença; Hipoglicemia/genética; Resistência à Insulina/genética; Defeitos do Tubo Neural/genética; Polimorfismo de Nucleotídeo Único; Adulto; Feminino; Feto; Interação Gene-Ambiente; Variação Genética; Glucose/metabolismo; Humanos; Modelos Logísticos; Masculino; Mães; Gravidez; Fatores de Risco; Adulto Jovem

Palavras-chave

BMI; Birth defects; CATI; CI; FDR; GWAS; Genegene interactions; LRT; Maternal genetics; Metabolic genes; NBDPS; NTDs; National Birth Defects Prevention Study; Neural tube defects; RR; SNP; body mass index; computer assisted telephone interview; confidence interval; false discovery rate; genome-wide association study; likelihood ratio test; neural tube defects; risk ratio; single nucleotide polymorphism

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Resistência à Insulina / Predisposição Genética para Doença / Polimorfismo de Nucleotídeo Único / Hipoglicemia / Defeitos do Tubo Neural Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Pregnancy Idioma: En Revista: Mol Genet Metab Ano de publicação: 2014 Tipo de documento: Article

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