Boundary coding in the rat subiculum.
Philos Trans R Soc Lond B Biol Sci
; 369(1635): 20120514, 2014 Feb 05.
Article
em En
| MEDLINE
| ID: mdl-24366128
ABSTRACT
The spatial mapping function of the hippocampal formation is likely derived from two sets of information one based on the external environment and the other based on self-motion. Here, we further characterize 'boundary vector cells' (BVCs) in the rat subiculum, which code space relative to one type of cue in the external environment boundaries. We find that the majority of cells with fields near the perimeter of a walled environment exhibit an additional firing field when an upright barrier is inserted into the walled environment in a manner predicted by the BVC model. We use this property of field repetition as a heuristic measure to define BVCs, and characterize their spatial and temporal properties. In further tests, we find that subicular BVCs typically treat drop edges similarly to walls, including exhibiting field repetition when additional drop-type boundaries are added to the testing environment. In other words, BVCs treat both kinds of edge as environmental boundaries, despite their dissimilar sensory properties. Finally, we also report the existence of 'boundary-off cells', a new class of boundary-coding cells. These cells fire everywhere except where a given BVC might fire.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
1_ASSA2030
Base de dados:
MEDLINE
Assunto principal:
Percepção Espacial
/
Sinais (Psicologia)
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Potenciais Evocados
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Hipocampo
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Modelos Neurológicos
/
Neurônios
Tipo de estudo:
Health_economic_evaluation
/
Prognostic_studies
Limite:
Animals
Idioma:
En
Revista:
Philos Trans R Soc Lond B Biol Sci
Ano de publicação:
2014
Tipo de documento:
Article