A review of maternally inherited diabetes and deafness.

Li, Hui-Zhen; Li, Rui-Yu; Li, Meng

Li, Hui-Zhen; Li, Rui-Yu; Li, Meng.

Afiliação

Li HZ; Institute for Integrated Traditional and Western Medicine, the Second Affiliated Hospital of Xingtai Medical College, Xingtai 054000, Hebei Province, China.
Li RY; Institute for Integrated Traditional and Western Medicine, the Second Affiliated Hospital of Xingtai Medical College, Xingtai 054000, Hebei Province, China.
Li M; Department of Health, Hotan Detachment of the Xinjiang Armed Police Corps, Hotan 848011, Xinjiang Uygur Autonomous Region, China.

Front Biosci (Landmark Ed) ; 19(5): 777-82, 2014 01 01.

Article em En | MEDLINE | ID: mdl-24389221

ABSTRACT

ABSTRACT

Maternally inherited diabetes and deafness (MIDD), a mitochondrial disease first described in 1992, results from the mitochondrial DNA mutation and affects up to 1% of the patients with diabetes. This review discusses the biomedical mechanisms of MIDD patients; summarizes the recent improvement of clinical and genetic diagnosis of MIDD; outlines the advances of the clinical management of these patients and their families.

Assuntos

Surdez/diagnóstico; Diabetes Mellitus Tipo 2/diagnóstico; DNA Mitocondrial/genética; Surdez/genética; Surdez/fisiopatologia; Surdez/terapia; Diabetes Mellitus Tipo 2/genética; Diabetes Mellitus Tipo 2/fisiopatologia; Diabetes Mellitus Tipo 2/terapia; Feminino; Humanos; Doenças Mitocondriais; Técnicas de Diagnóstico Molecular; Mutação; Gravidez

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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Surdez / Diabetes Mellitus Tipo 2 Tipo de estudo: Diagnostic_studies Limite: Female / Humans / Pregnancy Idioma: En Revista: Front Biosci (Landmark Ed) Ano de publicação: 2014 Tipo de documento: Article

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