Structure and dynamics of one-dimensional ionic solutions in biological transmembrane channels.
Biophys J
; 51(6): 969-76, 1987 Jun.
Article
em En
| MEDLINE
| ID: mdl-2440485
ABSTRACT
The structure and dynamics of solvated alkali metal cations in transmembrane channels are treated using the molecular dynamics simulation technique. The simulations are based on a modified Fischer-Brickmann model (Fischer, W., and J. Brickmann, 1983, Biophys. Chem., 18323-337) for gramicidin A-type channels. The trajectories of all particles in the channel as well as two-dimensional pair correlation functions are analyzed. It is found from the analysis of the stationary simulation state that one-dimensional solvation complexes are formed and that the number of water molecules in the channel varies for different alkali metal cations.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Canais Iônicos
/
Modelos Biológicos
Idioma:
En
Revista:
Biophys J
Ano de publicação:
1987
Tipo de documento:
Article