Endometrial hyperplasia: a clinicopathological study in a tertiary care hospital.
J Obstet Gynaecol India
; 63(6): 394-8, 2013 Dec.
Article
em En
| MEDLINE
| ID: mdl-24431686
ABSTRACT
OBJECTIVE:
To evaluate the clinical as well as histomorphologic features in different cases of endometrial hyperplasia along with its relative occurrence. MATERIALS ANDMETHODS:
A one-and-a-half-year prospective study was conducted on histopathologically diagnosed cases of endometrial hyperplasia in a tertiary care hospital. Apart from relevant clinical findings, histomorphologic details were noted and statistically analyzed. OBSERVATIONS Maximum number (46.5 %) of endometrial hyperplasia occurred in patients of 41-50 years age group. Majority (55.2 %) of the patients were found to be premenopausal. Menorrhagia was the most common (49.6 %) clinical presentation followed by postmenopausal bleeding (30.8 %). Simple hyperplasia without atypia was the most common type (95.6 %) followed by complex hyperplasia without atypia (3.6 %) and complex hyperplasia with atypia (0.8 %), respectively. The study of gland-stroma ratio revealed 6535 to be the most frequent (34 %) ratio; variable-sized glands with cystic dilatation (60.4 %) was the commonest gland architecture and most of the cases (99.2 %) showed the absence of atypia. Associated histopathological findings included a case each of endometrial adenocarcinoma and undifferentiated endometrial stromal sarcoma along with the common leiomyoma and progesterone effects.CONCLUSION:
Menorrhagia was the most common presenting complaint in cases of endometrial hyperplasia. The cases were mostly in the premenopausal age group. Simple endometrial hyperplasia without atypia was the commonest type diagnosed histopathologically. Histopathological examination along with clinical details is essential to give the final opinion regarding the diagnosis.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Idioma:
En
Revista:
J Obstet Gynaecol India
Ano de publicação:
2013
Tipo de documento:
Article