Incidence and metastasis of cutaneous malignant melanoma with respect to ABO blood groups: a case-controlled study in northeast of China.
PLoS One
; 9(2): e88096, 2014.
Article
em En
| MEDLINE
| ID: mdl-24516588
ABSTRACT
BACKGROUND:
ABO blood groups have been suggested to contribute to the development of certain tumors; however, the associations between ABO blood groups and the incidence and metastases of cutaneous malignant melanomas have not been fully evaluated in Chinese populations. Thus, we investigated these associations with a case-controlled study in northeast of China.METHODS:
A total of 482 patients with cutaneous malignant melanoma and 3,068 healthy- controls were enrolled for the study between 2001 and 2012 at The Tumor Hospital of Harbin Medical University. A multivariate logistic model was used to evaluate adjusted odds ratios (ORs) and 95% confidence intervals (CI) for the incidence and metastases of cutaneous malignant melanoma.RESULTS:
Blood type A individuals had higher tumor incidence and metastasis compared to those with blood type O (ORâ=â1.575; 95% CIâ=â1.208-2.053, pâ=â0.001; ORâ=â2.004; 95% CIâ=â1.032-3.889, pâ=â0.040), after adjusting for age, gender, smoking status and alcohol consumption.CONCLUSIONS:
Blood type A was associated with higher incidence and metastasis of cutaneous malignant melanoma but future studies are needed to examine the mechanisms linking cutaneous malignant melanoma to ABO blood types.
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
1_ASSA2030
/
2_ODS3
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8_ODS3_consumo_sustancias_psicoactivas
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Cutâneas
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Sistema ABO de Grupos Sanguíneos
/
Melanoma
Tipo de estudo:
Incidence_studies
/
Observational_studies
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Prognostic_studies
/
Risk_factors_studies
Limite:
Aged
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Female
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Humans
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Male
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Middle aged
País/Região como assunto:
Asia
Idioma:
En
Revista:
PLoS One
Ano de publicação:
2014
Tipo de documento:
Article