The early administration of Lactobacillus reuteri DSM 17938 controls regurgitation episodes in full-term breastfed infants.
Int J Food Sci Nutr
; 65(5): 646-8, 2014 Aug.
Article
em En
| MEDLINE
| ID: mdl-24635827
ABSTRACT
Forty breastfed full-term infants were randomly, double blind assigned to receive orally Lactobacillus reuteri (L. reuteri) DSM 17938, 5 drops/daily (10(8) colony-forming units), for 4 weeks (n = 20) or an identical placebo (n = 20), starting before third day of life. They underwent basal and final visit to monitor growth parameters and gastrointestinal (GI) disease. Parents registered daily crying minutes, stool frequency and consistency, numbers of regurgitations, adverse events. Secretory IgA (sIgA) has been measured in saliva on 28th day. Treated infants demonstrated a reduction in daily regurgitations at the end of treatment (p = 0.02), three neonates in the placebo group only needed simethicone for GI pain, sIgA level was similar in both groups. Random casualty produced an unbalanced gender distribution in the groups, but this bias did not affect the results. Therefore, early administration of L. reuteri DSM 17938 resulted beneficial in preventing regurgitation episodes during the first month of life.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
1_ASSA2030
/
2_ODS3
Base de dados:
MEDLINE
Assunto principal:
Aleitamento Materno
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Probióticos
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Limosilactobacillus reuteri
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Refluxo Laringofaríngeo
Tipo de estudo:
Clinical_trials
Limite:
Female
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Humans
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Male
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Newborn
Idioma:
En
Revista:
Int J Food Sci Nutr
Ano de publicação:
2014
Tipo de documento:
Article