Immunocytochemical evidence for substance P and serotonin input to medullary bulbospinal adrenergic neurons.
Synapse
; 2(6): 569-76, 1988.
Article
em En
| MEDLINE
| ID: mdl-2463693
ABSTRACT
Using two-color immunoperoxidase staining combined with the retrograde transport of horseradish peroxidase injected into the rostral thoracic spinal cord, substance P-immunoreactive (SPI) and serotonin-immunoreactive (5HTI) varicosities have been observed in contiguity with medullary bulbospinal phenylethanolamine N-methyl transferase-immunoreactive (PNMTI) neurons of the C1, C2, and C3 cell groups. Since PNMTI terminals in the spinal cord are concentrated among sympathetic preganglionic neurons (SPGN) in the intermediolateral cell column, the close anatomical associations shown in the present study indicate that substance P- and serotonin-containing pathways in the medulla likely affect activity of SPGN via adrenergic bulbospinal neurons.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Feniletanolamina N-Metiltransferase
/
Medula Espinal
/
Bulbo
/
Serotonina
/
Substância P
/
Fibras Adrenérgicas
Limite:
Animals
Idioma:
En
Revista:
Synapse
Ano de publicação:
1988
Tipo de documento:
Article