Competition between Plasmodium falciparum strains in clinical infections during in vitro culture adaptation.

Chen, Kexuan; Sun, Ling; Lin, Yingxue; Fan, Qi; Zhao, Zhenjun; Hao, Mingming; Feng, Guohua; Wu, Yanrui; Cui, Liwang; Yang, Zhaoqing

Chen, Kexuan; Sun, Ling; Lin, Yingxue; Fan, Qi; Zhao, Zhenjun; Hao, Mingming; Feng, Guohua; Wu, Yanrui; Cui, Liwang; Yang, Zhaoqing.

Afiliação

Chen K; Department of Pathogen Biology and Immunology, Kunming Medical University, Yunnan Province 650500, China.
Sun L; Department of Pathogen Biology and Immunology, Kunming Medical University, Yunnan Province 650500, China.
Lin Y; Center for Disease Control and Prevention, Yingjiang, Yunnan Province 679300, China.
Fan Q; Dalian Institute of Biotechnology, Dalian, Liaoning Province, China.
Zhao Z; Dalian Institute of Biotechnology, Dalian, Liaoning Province, China.
Hao M; Department of Pathogen Biology and Immunology, Kunming Medical University, Yunnan Province 650500, China.
Feng G; Center for Biomedical Engineering Research, Kunming Medical University, Yunnan Province 650500, China.
Wu Y; Department of Cell Biology and Genetics, Kunming Medical University, Yunnan Province 650500, China.
Cui L; Department of Entomology, The Pennsylvania State University, 501 ASI Bldg., University Park, PA 16802, USA. Electronic address: luc2@psu.edu.
Yang Z; Department of Pathogen Biology and Immunology, Kunming Medical University, Yunnan Province 650500, China. Electronic address: zhaoqingy@yahoo.com.

Infect Genet Evol ; 24: 105-10, 2014 Jun.

Article em En | MEDLINE | ID: mdl-24667050

Assuntos

Malária Falciparum/tratamento farmacológico; Proteína 1 de Superfície de Merozoito/genética; Proteínas Associadas à Resistência a Múltiplos Medicamentos/genética; Plasmodium falciparum/genética; Tetra-Hidrofolato Desidrogenase/genética; Alelos; Antígenos de Protozoários/genética; Antimaláricos/uso terapêutico; Artemisininas/uso terapêutico; DNA de Protozoário/genética; Resistência a Medicamentos/genética; Variação Genética; Genótipo; Humanos; Malária Falciparum/patologia; Plasmodium falciparum/classificação; Plasmodium falciparum/isolamento & purificação; Proteínas de Protozoários/genética; Quinolinas/uso terapêutico

Palavras-chave

Culture adaptation; Drug resistance; Fitness cost; In vitro competition; Mixed infection; Plasmodium falciparum

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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 2_ODS3 / 3_ND Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Tetra-Hidrofolato Desidrogenase / Malária Falciparum / Proteína 1 de Superfície de Merozoito / Proteínas Associadas à Resistência a Múltiplos Medicamentos Limite: Humans Idioma: En Revista: Infect Genet Evol Ano de publicação: 2014 Tipo de documento: Article

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