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HIF prolyl 4-hydroxylase-2 inhibition improves glucose and lipid metabolism and protects against obesity and metabolic dysfunction.
Rahtu-Korpela, Lea; Karsikas, Sara; Hörkkö, Sohvi; Blanco Sequeiros, Roberto; Lammentausta, Eveliina; Mäkelä, Kari A; Herzig, Karl-Heinz; Walkinshaw, Gail; Kivirikko, Kari I; Myllyharju, Johanna; Serpi, Raisa; Koivunen, Peppi.
Afiliação
  • Rahtu-Korpela L; Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, Oulu Center for Cell-Matrix Research, University of Oulu, FIN-90014 Oulu, Finland.
  • Karsikas S; Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, Oulu Center for Cell-Matrix Research, University of Oulu, FIN-90014 Oulu, Finland.
  • Hörkkö S; Nordlab Oulu, Oulu University Hospital, FIN-90220 Oulu, Finland Department of Medical Microbiology and Immunology, Medical Research Center, University of Oulu, FIN-90014 Oulu, Finland.
  • Blanco Sequeiros R; Department of Radiology, Oulu University Hospital and University of Oulu, FIN-90029 Oulu, Finland.
  • Lammentausta E; Department of Radiology, Oulu University Hospital and University of Oulu, FIN-90029 Oulu, Finland.
  • Mäkelä KA; Biocenter Oulu, Department of Physiology, University of Oulu, FIN-90014 Oulu, Finland.
  • Herzig KH; Biocenter Oulu, Department of Physiology, University of Oulu, FIN-90014 Oulu, Finland.
  • Walkinshaw G; FibroGen, Inc., San Francisco, CA.
  • Kivirikko KI; Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, Oulu Center for Cell-Matrix Research, University of Oulu, FIN-90014 Oulu, Finland.
  • Myllyharju J; Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, Oulu Center for Cell-Matrix Research, University of Oulu, FIN-90014 Oulu, Finland.
  • Serpi R; Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, Oulu Center for Cell-Matrix Research, University of Oulu, FIN-90014 Oulu, Finland.
  • Koivunen P; Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, Oulu Center for Cell-Matrix Research, University of Oulu, FIN-90014 Oulu, Finland peppi.koivunen@oulu.fi.
Diabetes ; 63(10): 3324-33, 2014 Oct.
Article em En | MEDLINE | ID: mdl-24789921
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Síndrome Metabólica / Metabolismo dos Carboidratos / Metabolismo dos Lipídeos / Prolina Dioxigenases do Fator Induzível por Hipóxia / Glucose / Obesidade Limite: Animals Idioma: En Revista: Diabetes Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Síndrome Metabólica / Metabolismo dos Carboidratos / Metabolismo dos Lipídeos / Prolina Dioxigenases do Fator Induzível por Hipóxia / Glucose / Obesidade Limite: Animals Idioma: En Revista: Diabetes Ano de publicação: 2014 Tipo de documento: Article