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Insulin regulates carboxypeptidase E by modulating translation initiation scaffolding protein eIF4G1 in pancreatic ß cells.
Liew, Chong Wee; Assmann, Anke; Templin, Andrew T; Raum, Jeffrey C; Lipson, Kathryn L; Rajan, Sindhu; Qiang, Guifen; Hu, Jiang; Kawamori, Dan; Lindberg, Iris; Philipson, Louis H; Sonenberg, Nahum; Goldfine, Allison B; Stoffers, Doris A; Mirmira, Raghavendra G; Urano, Fumihiko; Kulkarni, Rohit N.
Afiliação
  • Liew CW; Joslin Diabetes Center and Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02215;Department of Physiology and Biophysics, University of Illinois at Chicago, Chicago, IL 60612; rohit.kulkarni@joslin.harvard.edu cwliew@uic.edu.
  • Assmann A; Joslin Diabetes Center and Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02215;
  • Templin AT; Department of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis, IN 46202;
  • Raum JC; Department of Medicine/Endocrinology, Diabetes, and Metabolism and the Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104;
  • Lipson KL; Program in Gene Function and Expression, University of Massachusetts Medical School, Worcester, MA 01605;
  • Rajan S; Department of Medicine, The University of Chicago, Chicago, IL 60637;
  • Qiang G; Department of Physiology and Biophysics, University of Illinois at Chicago, Chicago, IL 60612;
  • Hu J; Joslin Diabetes Center and Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02215;
  • Kawamori D; Joslin Diabetes Center and Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02215;
  • Lindberg I; Department of Anatomy and Neurobiology, University of Maryland, Baltimore, MD 21201;
  • Philipson LH; Department of Medicine, The University of Chicago, Chicago, IL 60637;
  • Sonenberg N; Department of Biochemistry, McGill University, Montreal, QC, Canada H3A 1A3; and.
  • Goldfine AB; Joslin Diabetes Center and Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02215;
  • Stoffers DA; Department of Medicine/Endocrinology, Diabetes, and Metabolism and the Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104;
  • Mirmira RG; Department of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis, IN 46202;
  • Urano F; Division of Endocrinology, Metabolism, and Lipid Research, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110.
  • Kulkarni RN; Joslin Diabetes Center and Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02215; rohit.kulkarni@joslin.harvard.edu cwliew@uic.edu.
Proc Natl Acad Sci U S A ; 111(22): E2319-28, 2014 Jun 03.
Article em En | MEDLINE | ID: mdl-24843127
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator de Iniciação Eucariótico 4G / Carboxipeptidase H / Diabetes Mellitus Tipo 2 / Células Secretoras de Insulina / Insulina Limite: Animals / Humans / Male Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator de Iniciação Eucariótico 4G / Carboxipeptidase H / Diabetes Mellitus Tipo 2 / Células Secretoras de Insulina / Insulina Limite: Animals / Humans / Male Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2014 Tipo de documento: Article